Insights

Defining the category, in the open.

Opinion and thought leadership from our scientists — on the gut-brain axis, precision modulation of the microbiome, the biology of keystone gut species, and what "evidence" should mean for functional ingredients.

The brain is not sealed
Insight · 7 min read

The brain is not sealed

The immune cells defending your brain were supposed to last a lifetime. New human data shows they start being replaced around fifty, and the replacements are educated somewhere unexpected.
Patrick Guye
A remote control for memory, hidden in the gut
Brain Health · 4 min read

A remote control for memory, hidden in the gut

A new Nature paper shows an aging gut can drive memory loss on its own — and reverse it. The twist is which molecule does the damage.
Trilliome Staff
A GLP-1 drug treated depression without touching its receptor
Science · 5 min read

A GLP-1 drug treated depression without touching its receptor

A GLP-1 drug relieved depression in mice with its receptor deleted. The effect ran through a single gut bacterium, not the brain. What the science says about the gut microbiome and mental health, and where it doesn't.
Patrick Guye
Beyond biotics: the case for precision bioactives
Insight · 2 min read

Beyond biotics: the case for precision bioactives

Probiotics add live bacteria; fibre feeds them in bulk. Our co-founder Tim Mak told Fi Global about a third path — plant-derived bioactives that reprogramme the gut bacteria a person already carries.
Trilliome Staff
The window for fixing the gut-brain axis closes earlier than we thought
Brain Health · 4 min read

The window for fixing the gut-brain axis closes earlier than we thought

Patrick Guye
Diversity is key to a healthy gut
nutrition · 3 min read

Diversity is key to a healthy gut

Nutrition & Longevity: Walking through Hong Kong's markets—greens, reds, purples, and yellows—highlights a vital truth: diversity in diet is essential for a healthy gut and overall well-being.
Patrick Guye
Biotech: Building a Commercial Culture: Embrace commercial innovation early, even if it requires leadership changes.
Insight · 1 min read

Biotech: Building a Commercial Culture: Embrace commercial innovation early, even if it requires leadership changes.

Patrick Guye